Waldenstrom ' s Macroglobulinaemia Presenting as Demyelinating Polyradiculoneuropathy SAW

نویسنده

  • S K Cheong
چکیده

WM is an unusual low-grade lymphoplasmacytic lymphoma characterised by proliferation of malignant lymphocytoid cells in the bone marrow and lymph nodes that secretes monoclonal IgM. WM typically .affects elderly men who usually present with systemic symptoms of fatigue, anaemia, bleeding and hyperviscosity. Peripheral neuropathy occurs in approximately one-third of patients with WM. Polyneuropathy associated with WM is usually of gradual onset, symmetrical and predominantly sensory!. However, in the present case, the associated polyneuropathy was subacute in onset, progressive and predominantly motor. This type of neuropathy in patients with WM is presumably very rare.

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تاریخ انتشار 2011